1. Nā mea kū'ē i ka Endothelin
Lawe ʻia ia mai ka chamomile herb European, hiki ke pale i ka endothelin a keʻakeʻa i ka hana ʻana o nā melanocytes.ʻO ka māhele like ʻole o ka endothelin i ka ʻili ke kumu nui e alakaʻi ai i ka hoʻokumu ʻana o ka pigmentation.Hiki i ka Endothelin antagonists ke kāohi i ka endothelin.. tyrosinase a hoʻoikaika i ka ʻokoʻa o nā melanocytes.
Ua ʻike nā haʻawina he haʻahaʻa ka cytotoxicity o ka endothelin antagonists i unuhi ʻia mai nā meaola wai a hiki ke kāohi i ka ʻokoʻa o ka endothelin ma nā melanocytes a me ka hana o tyrosinase.ʻO nā maʻi hyperpigmentation o ka ʻili ma muli o ka hoʻonui -l hiki ke loaʻa i nā manaʻo noi.
2. ʻO Resveratrol a me kāna mau mea i loaʻa
ResveratrolAia ka nui i loko o nā hua waina, Polygonum cuspidatum, Veratrum a me nā mea kanu ʻē aʻe, a ke kāohi nei i ka hana o nā melanocytes a me ka hana o tyrosinase i ke ʻano hilinaʻi, e hōʻemi ana i ka synthesis melanin.Ua ʻike ʻo Jeong et al ua pili pū me nā protein pili tyrosinase i ka melanogenesis.
Ua hōʻike ʻo Jia Lili a me nā haʻawina ʻē aʻe e hiki i ka resveratrol topical ke hoʻomaikaʻi maikaʻi i ka waihoʻoluʻu ʻili, loaʻa kahi hopena keʻokeʻo, a ʻaʻohe hopena ʻino.Loaʻa ka Resveratrol i nā hemahema o ka instability a me ka bioavailability maikaʻi ʻole.Ua ʻike nā haʻawina ʻo kāna mau derivatives (pentaalkyl ether derivatives a me tetraester derivatives) he bioavailability kiʻekiʻe a hiki ke kāohi maikaʻi i ka synthesis o melanin.Loaʻa iā ia nā manaʻo noi ākea i nā mea hoʻonaninani keʻokeʻo.
3. Kamelika Extract
ʻO Camellia ka ʻohana Camellia o ka ʻohana Camellia.Nakamura et al.Ua ʻike ʻia ʻo ka ʻōpala pua camellia hiki ke kāohi i ka hana melanin a hoʻoikaika i ka ʻokoʻa fibroblast.Ua hoʻoholo ʻo Huang Xiaofeng a me nā haʻawina ʻē aʻe he ʻoi aku ka maikaʻi o ka lālā kī a Dianshan ma mua o arbutin ma ke ʻano o ka hoʻonui ʻana o ke kelepona a me ka hoʻopaʻa ʻana i ka hana tyrosinase, a ʻoi aku ka maikaʻi o nā waiwai ma mua o arbutin.He ʻano hou ia o ka ʻili keʻokeʻo keʻokeʻo a loaʻa i kahi ākea o nā noi.manaʻolana.
MelaninSynthaseImea hōʻole
1. Arbutin
He mea koʻikoʻi ia o ka tyrosinase inhibitor, hiki ke pale i ka hana o tyrosinase, ālai i ka synthesis o dopa a me dopaquinone, a laila e pale ai i ka hana ʻana o ka melanin, a hiki ke hoʻemi nui i ka pigmentation i hana ʻia e nā kukui ultraviolet, akā paʻa ka hana maikaʻi ʻole, me kekahi. kiʻi kiʻi.
Ua ʻike ʻia ka haʻawina ʻo ka arbutin me ka hoʻopaʻa ʻana o 3% he mau waiwai maikaʻi, haʻahaʻa cytotoxicity, irritation a me ka allergy, a ʻo ka palena kiʻekiʻe o kona ʻike ʻaʻole hiki ke ʻoi aku ma mua o 7%.ʻO kahi kiʻekiʻe o ka arbutin e decolorize i ka ʻili maʻamau.ʻO kāna mea hana maoli, ʻo glucopyranoside, ʻoi aku ka ikaika o ka pale ʻana i ka tyrosinase kanaka ma mua o ka arbutin, a pani i ka arbutin no ka mea ʻoi aku ka maikaʻi a paʻa.
2. Laki Laki
ʻO kāna mau mea hana he liquiritin, isoliquiritin a me nā flavonoids licorice.Hana ʻo Liquiritin i ka melanin o ka ʻili ma ka hoʻopuehu ʻana i ka melanin aggregated, a loaʻa ka hopena keʻokeʻo;ʻO ka hana nui o nā flavonoids licorice ke kāohi i ka hana o tyrosinase, DHICA oxidase a me dopa pigment intermutase.
Ua ʻike nā haʻawina ʻo nā huahana mālama ʻili lapaʻau i loaʻa i ka licorice extract a me ka papain hiki ke kōkua i ka melasma a me ka hyperpigmentation post-inflammatory, me ka liʻiliʻi o nā hopena ʻino, a loaʻa kekahi .. a me .. waiwai.ʻO kona koʻikoʻi i nā huahana keʻokeʻo he 10% a 40%, akā ʻaʻole kiʻekiʻe ka ʻike o nā mea hana i ka licorice a paʻakikī a paʻakikī ka hoʻomaʻemaʻe.
3. ʻO Chuanxiong Extract
Ua ʻike nā haʻawina ʻo Chuanxiong extract hiki ke kāohi pono i ka hana o tyrosinase, e hōʻike ana i kahi hopena inhibitory hoʻokūkū.Ua hoʻomohala ʻia ka ʻaila ʻo Chuanqiong ma o ka hui pū ʻana o nā emulsifiers like ʻole a me nā mānoanoa like ʻole, ua hōʻike ka noiʻi e pili ana i kona pono keʻokeʻo a me ka hana ʻana i ka 0.5% ~ 1.0% ʻo Chuanqiong hinu i nā hiʻohiʻona o ke kūpaʻa maikaʻi, ka hana kiʻekiʻe a me ka hopena keʻokeʻo maikaʻi.
ʻO Salidroside a me flavonoids kāna mau mea hana nui, a hiki i ka salidroside ke hōʻino i nā lipids a me nā membrane cell e nā kukuna ultraviolet.Hiki i ka extract ke kāohi i ka synthesis o ka melanin a me ka hana o tyrosinase, a he mea hoʻomaʻemaʻe ʻili maikaʻi.Ua ʻike ʻia ka haʻawina ʻo 1% a me 5% o Rhodiola rosea extract ʻaʻole i hana i nā hopena ʻino i ke kino o ke kanaka, a he mea hana hoʻonaninani me ke kūpaʻa kiʻekiʻe a loaʻa ka manaʻo ākea i nā noi hoʻonaninani.
5. Aloina
He glycoprotein mea kanu kaumaha haʻahaʻa i lawe ʻia mai ka aloe vera.Hoʻopaʻa nui ia i ka hoʻokumu ʻana o dopaquinone ma ka hoʻokūkū hoʻokūkū i ka dopa oxidation site, a hoʻokō i ka hoʻokūkū hoʻokūkū ʻole ma ka hoʻokūkū hoʻokūkū i nā ion keleawe ma ka pūnaewele hydroxylase.ʻO ka hana o tyrosine hydroxylase.Eia kekahi, hiki i ka aloin ke hoʻemi i ka ʻeleʻele o ka ʻili ma muli o nā kukuna ultraviolet, a he hopena hoʻoponopono maikaʻi i ka ʻili ma hope o ka ʻike ʻana o ka lā.ʻO ka aloin he hydrophilic a me ka non-cytotoxic.Hiki i ka hui ʻana i ka aloin me ka arbutin ke hoʻomaikaʻi i ka hopena keʻokeʻo.
Loaʻa ia i ka ʻili, nā aʻa, nā lau a me nā hua o nā mea kanu, a ʻo kona hopena keʻokeʻo e pili nui ana i kona absorption o nā kukui ultraviolet, antioxidant elimination o nā radical manuahi, a me ka inhibition o tyrosinase a me nā hana peroxidase.ʻO ka waika Ellagic he polyphenol maoli i unuhi ʻia mai ka ʻili pomegerane, ka ʻili a me nā huaʻai a me nā mea kanu like ʻole.Hiki iā ia ke pale i ka hoʻonui ʻana o nā melanocytes, ke kāohi i ka hana o ka melanocyte tyrosinase, e hoʻemi i ka synthesis melanin, ʻo nā kukui Ultraviolet he hopena absorption ikaika, hiki ke pāʻani i ka pale ʻana i ka lā a i ʻole ka scavenging free radical ma o ka lawe ʻana i nā kukuna ultraviolet.ʻO ka mea kanu polyphenol kahi ʻano mea hana pono, nona nā manaʻo ākea no ka hoʻomohala ʻana a me ka hoʻohana ʻana i nā mea hoʻonaninani.
Nā kikoʻī pili:
Shaanxi Ruiwo Phytochem Co.,Ltd.
Luna Hoʻokele o nā ʻāina ʻē: Jason
Mob: 0086-18629669868
leka uila:jason@ruiwophytochem.com
Whatsapp: 008618629669868
Ka manawa hoʻouna: Iulai-13-2022
