1. Nā mea kū'ē i ka Endothelin

Ua unuhi ʻia mai ka chamomile lau nahele ʻEulopa, hiki ke pale aku i ka endothelin a kāohi i ka hana ʻana o nā melanocytes. ʻO ka hoʻolaha like ʻole o ka endothelin i loko o ka ʻili ke kumu nui e alakaʻi ai i ka hoʻokumu ʻia ʻana o ka pigmentation. Hiki i nā antagonists Endothelin ke kāohi i ka endothelin.. tyrosinase a paipai i ka hoʻokaʻawale ʻana o nā melanocytes.

Ua ʻike ʻia nā haʻawina he haʻahaʻa ka cytotoxicity o nā antagonists endothelin i unuhi ʻia mai nā meaola wai a hiki ke kāohi i ka hoʻokaʻawale ʻana o ka endothelin ma nā melanocytes a me ka hana o ka tyrosinase. ʻO nā maʻi hyperpigmentation ʻili i hoʻokumu ʻia e ka hoʻonui ʻia o ka -l he mau manaʻolana noi paha.

2. ʻO Resveratrol a me kāna mau mea i loaʻa

ResveratrolLoaʻa nui ia i nā hua waina, Polygonum cuspidatum, Veratrum a me nā mea kanu ʻē aʻe, a kāohi i ka hana o nā melanocytes a me ka hana o ka tyrosinase ma ke ʻano e hilinaʻi ana i ka noʻonoʻo ʻana, a laila e hōʻemi ana i ka synthesis melanin. Ua ʻike ʻo Jeong et al ua pili pū ia me nā protein e pili ana i ka tyrosinase i ka melanogenesis.

Ua hōʻike ʻo Jia Lili a me nā haʻawina ʻē aʻe e hiki i ka resveratrol topical ke hoʻomaikaʻi maikaʻi i ke kala o ka ʻili, loaʻa kahi hopena keʻokeʻo, a ʻaʻohe hopena maikaʻi ʻole. Loaʻa iā Resveratrol nā hemahema o ka paʻa ʻole a me ka bioavailability haʻahaʻa. Ua ʻike ʻia nā haʻawina he kiʻekiʻe ka bioavailability o kāna mau derivatives (pentaalkyl ether derivatives a me tetraester derivatives) a hiki ke kāohi maikaʻi i ka synthesis o melanin. Loaʻa iā ia nā manaʻolana hoʻohana ākea i nā mea hoʻonaninani keʻokeʻo.

3. ʻO ka Camellia Extract

ʻO Camellia ka ʻano Camellia o ka ʻohana Camellia. Ua ʻike ʻo Nakamura et al. hiki i ka ʻōpuʻu pua camellia ke kāohi i ka hana ʻana o ka melanin a hoʻolaha i ka hoʻokaʻawale ʻana o ka fibroblast. Ua hoʻoholo ʻo Huang Xiaofeng a me nā haʻawina ʻē aʻe he ʻoi aku ka maikaʻi o ka lālā kī a me ka lau Dianshan ma mua o ka arbutin ma ke ʻano o ka hoʻonui ʻana o nā cell a me ka pale ʻana i ka hana tyrosinase, a he mau waiwai maikaʻi aʻe ma mua o ka arbutin. He ʻano hou ia o ka mea hoʻokeʻokeʻo ʻili a he ākea nā noi. manaʻolana.

MelaninaSynthaseImea kāohi

1. ʻArbutin

He mea hoʻopaʻa tyrosinase koʻikoʻi ia, hiki ke kāohi i ka hana o tyrosinase, ālai i ka synthesis o dopa a me dopaquinone, a laila e kāohi ana i ka hana ʻana o ka melanin, a hiki ke hōʻemi nui i ka pigmentation i hoʻokumu ʻia e nā kukuna ultraviolet, akā paʻa ia. Hana maikaʻi ʻole, me kekahi photosensitivity.

Ua ʻike ʻia ma ke aʻo ʻana he 3% nā waiwai maikaʻi o ka arbutin me ka nui o 3%, ka cytotoxicity haʻahaʻa, ka huhū a me ka allergy, a ʻaʻole hiki i ka palena kiʻekiʻe o kona nui ke ʻoi aku ma mua o 7%. ʻO ka nui o ka arbutin e hoʻopau i ke kala o ka ʻili maʻamau. ʻO kāna mea hana maoli, glucopyranoside, he hopena pale ikaika i ka tyrosinase kanaka ma mua o ka arbutin, a pani i ka arbutin no ka mea ʻoi aku ka maikaʻi a me ka paʻa.

2. ʻO ka Licorice Extract

ʻO kāna mau mea hana nui ka liquiritin, isoliquiritin a me nā flavonoids licorice. Hoʻolaha like ʻo Liquiritin i ka melanin ʻili ma ka hoʻopuehu ʻana i ka melanin i hōʻuluʻulu ʻia, a hoʻokō i ka hopena keʻokeʻo; ʻo ka hana nui o nā flavonoids licorice ka pale ʻana i ka hana o tyrosinase, DHICA oxidase a me ka dopa pigment intermutase.

Ua ʻike ʻia nā noiʻi e hiki i nā huahana mālama ʻili lapaʻau e loaʻa ana ka licorice extract a me ka papain ke kōkua i ka melasma a me ka hyperpigmentation post-inflammatory, me ka emi ʻana o nā hopena ʻino, a he mau waiwai .. a me .. kona ʻano i nā huahana keʻokeʻo he 10% a 40%, akā ʻaʻole kiʻekiʻe ka nui o nā mea hana i loko o ka licorice a he paʻakikī a pipiʻi hoʻi ka hoʻomaʻemaʻe ʻana.

3. ʻO Chuanxiong Extract

Ua ʻike ʻia nā haʻawina e hiki i ka ʻaila Chuanxiong ke kāohi pono i ka hana o ka tyrosinase, e hōʻike ana i kahi hopena hoʻokūkū. Ua hoʻomohala ʻia ka ʻaila Chuanqiong ma o ke ʻano hui o nā emulsifiers like ʻole a me nā thickeners like ʻole, ua hōʻike ka noiʻi ʻana i kona pono keʻokeʻo a me ka hana ʻana he 0.5% ~ 1.0% ka ʻaila Chuanqiong i nā ʻano o ke kūpaʻa maikaʻi, ka hana kiʻekiʻe a me ka hopena keʻokeʻo maikaʻi.

4. ʻO ka Rhodiola Rosea Extract

ʻO Salidroside a me nā flavonoids kāna mau mea hana nui, a hiki i ka salidroside ke hōʻino i nā lipids a me nā membrane cell e nā kukuna ultraviolet. Hiki i ka extract ke kāohi i ka synthesis o ka melanin a me ka hana o tyrosinase, a he mea hoʻokeʻokeʻo ʻili maikaʻi. Ua ʻike ʻia ma ke aʻo ʻana ʻaʻole i hoʻoulu ka 1% a me 5% o ka Rhodiola rosea extract i nā hopena maikaʻi ʻole i ke kino o ke kanaka, a he mea hana hoʻonaninani me ke kūpaʻa kiʻekiʻe a he manaʻolana ākea i nā noi hoʻonaninani.

5. ʻAloina

He glycoprotein mea kanu kaumaha haʻahaʻa i unuhi ʻia mai ka aloe vera. Hoʻopaʻa nui ia i ka hoʻokumu ʻia ʻana o ka dopaquinone ma ka hoʻokūkū hoʻopaʻa ʻana i ka pūnaewele oxidation dopa, a hoʻokō i ka pale ʻole hoʻokūkū ma ka hoʻokūkū hoʻopaʻa ʻana i nā ion keleawe ma ka pūnaewele hydroxylase. ʻO ka hana o ka tyrosine hydroxylase. Eia kekahi, hiki i ka aloin ke hōʻemi i ka ʻeleʻele o ka ʻili i hoʻokumu ʻia e nā kukuna ultraviolet, a he hopena hoʻoponopono maikaʻi i ka ʻili ma hope o ka ʻike ʻana i ka lā. He hydrophilic a ʻaʻole cytotoxic ka Aloin. ʻO ka hui ʻana i ka aloin me ka arbutin hiki ke hoʻomaikaʻi i ka hopena keʻokeʻo.

6. Nā Polyphenols Mea kanu

Loaʻa nui ia i loko o ka ʻili lāʻau, nā aʻa, nā lau a me nā hua o nā mea kanu, a ʻo kona hopena keʻokeʻo e pili nui ana i kona omo ʻana i nā kukuna ultraviolet, ka hoʻopau ʻana i nā radical manuahi me ka antioxidant, a me ka pale ʻana i nā hana tyrosinase a me peroxidase. ʻO ka waikawa Ellagic kahi polyphenol kūlohelohe i unuhi ʻia mai ka ʻili pomegranate, ka ʻili lāʻau a me nā huaʻai a me nā mea kanu like ʻole. Hiki iā ia ke kāohi i ka hoʻolaha ʻana o nā melanocytes, kāohi i ka hana o ka melanocyte tyrosinase, hōʻemi i ka synthesis melanin, Loaʻa i nā kukuna Ultraviolet kahi hopena omo ikaika, hiki ke pāʻani i kahi kuleana i ka pale ʻana i ka lā a i ʻole ka scavenging free radicals ma ka omo ʻana i nā kukuna ultraviolet. ʻO ka polyphenol mea kanu kahi ʻano mea hana kūpono, nona nā manaʻolana ākea no ka hoʻomohala ʻana a me ka hoʻohana ʻana i nā mea hoʻonani.

ʻIke pili:
Shaanxi Ruiwo Phytochem Co.,Ltd.
Luna Hoʻokele ma waho: Jason
Pūʻulu: 0086-18629669868
Leka uila:jason@ruiwophytochem.com
Whatsapp: 008618629669868