ʻO ka maʻi kanesa ka lua o ka maʻi kanesa maʻamau ma ka honua. Ma 2020, ʻoi aku ma mua o 2.2 miliona mau kānaka i ka honua holoʻokoʻa e ʻike ʻia me ka maʻi maʻi maʻi maʻi no ka manawa mua. I ka makahiki hoʻokahi, ma kahi o 1.8 miliona mau kānaka i make i ka maʻi kanesa maʻi.
ʻOiai ʻaʻohe lāʻau lapaʻau i kēia manawa no ka maʻi maʻi ʻāʻī, ke hana nei nā ʻepekema i nā koho lapaʻau. Ke hana nei kekahi o kēia poʻe ʻepekema ma ke Kulanui o Technology Sydney (UTS), kahi i hōʻike ʻia ai kahi noiʻi hou e hiki i kahi mea kanu kūlohelohe i kapa ʻia ʻo berberine hiki ke hoʻōki i ka ulu ʻana o nā maʻi maʻi maʻi maʻi i loko o ka hale hana.
ʻO Berberine kahi mea kanu kūlohelohe i hoʻohana ʻia i ka lāʻau lapaʻau Kina no nā kaukani makahiki. Loaʻa ia i loko o nā ʻano mea kanu like ʻole, me ka barberry, goldenseal, Oregon grape, a me ka turmeric lāʻau.

(ʻO kā mākou huahanaHua'ala Berberine, hoʻokipa maikaʻi i ka nīnau.)

Ua hōʻike ʻia nā makahiki o ka noiʻi ʻana he maikaʻi ka berberine i ke kōkua ʻana i ka poʻe me ka maʻi maʻi type 2 e hoʻoponopono i ko lākou pae kō koko a hiki ke kōkua i ka mālama ʻana i ka metabolic syndrome.
Ua ʻike pū nā mea noiʻi hiki ke hoʻohana ʻia ka berberine no ka mālama ʻana i nā maʻi maʻi like ʻole, e like me ka ovarian, ʻōpū, a me ka maʻi maʻi umauma.
E like me ka Dr. Kamal Dua, Senior Lecturer a me Senior Research Fellow ma Pharmacy ma ka Australian Research Center for Complementary and Integrative Medicine (ARCCIM), University of Technology Sydney (UTS) School of Medicine a alakaʻi kumu o ka noiʻi, Berberine inhibits elua kī nā kaʻina hana i ka hoʻomohala ʻana i ka maʻi kanesa - Proliferation and cell migration.
"Ma ka mīkini, hiki ke hoʻokō ʻia kēia ma ke kāohi ʻana i nā genes nui e like me P53, PTEN a me KRT18 a me nā protein e like me AXL, CA9, ENO2, HER1, HER2, HER3, PRGN, PDGF-AA, DKK1, CTSB, CTSD, BCLX, CSF1. a me CAPG pili i ka hoʻonui a me ka neʻe ʻana o nā maʻi maʻi maʻi, "i wehewehe ʻo ia.
Ma ka noiʻi o kēia manawa, kahi hui noiʻi me Dr. Dua, Dr. Keshav Raj Paudel, Professor Philip M. Hansbrough a me Dr. Bikash Manandhar o UTS, a me nā limahana mai ka Malaysian International Medical University a me Al Qasim University ma Saudi Arabia, ua aʻo pehea e hoʻohana ʻia ai ka berberine i ka mālama ʻana i ka maʻi kanesa.
"Hoʻohana ʻia ka hoʻohana ʻana i ka berberine ma muli o ka maikaʻi ʻole o ka solubility a me ka bioavailability," wehewehe ʻo Dr. Dua no MNT. "ʻO ka pahuhopu nui o kēia noiʻi ʻana ʻo ka hoʻomaikaʻi ʻana i nā ʻāpana physicochemical o berberine ma ka hoʻohuli ʻana i ka berberine i loko o nā nanoparticles kristal wai a e ʻimi i kona hiki ke anticancer in vitro ma nā cell basal epithelial alveolar o ke kanaka adenocarcinoma A549."
Ua hoʻomohala ka hui noiʻi i kahi ʻōnaehana hoʻopuka lāʻau holomua e hoʻopili ai i ka berberine i nā pōʻai liʻiliʻi hiki ke hoʻoheheʻe ʻia. Ua hoʻohana ʻia kēia mau nanoparticles kristal wai no ka mālama ʻana i nā maʻi maʻi maʻi maʻi kanaka i vitro i loko o ka hale hana.
I ka pau ʻana o ke aʻo ʻana, ua ʻike ka hui ua kōkua ka berberine i ka hana ʻana i nā ʻano oxygen reactive, nā kemika inflammatory i hana ʻia e kekahi mau cell i ka pane ʻana i ka hoʻouka kaua bacteria a me nā hanana koʻikoʻi ʻē aʻe e hiki ke hōʻino i nā cell.
Eia kekahi, kōkua ka berberine i ka hoʻoponopono ʻana i nā genes e pili ana i ke koʻikoʻi oxidative a me ka mumū, a kōkua i ka hōʻemi ʻana i ka ʻelemakule cell premature.
"Ua hōʻike mākou, me ka hoʻohana ʻana i kahi ʻano nanotechnological, hiki ke hoʻomaikaʻi ʻia nā waiwai o ka pūhui e hoʻoponopono i nā pilikia like ʻole e pili ana i ka solubility, ka lawe ʻana i ke kelepona, a me ka pono therapeutic," wehewehe ʻo Dr. Dua. Hiki i ka Anticancer ʻO kā mākou berberine liquid crystal nanoparticles i hōʻike i ka hana like i ʻelima mau manawa i ka nui o ka nui i hoʻohālikelike ʻia i nā palapala i paʻi ʻia, e hōʻike pono ana i nā pono o nā nanodrugs.
No ka hoʻāʻo hou ʻana i kēia mau hopena, ua ʻōlelo ʻo Kauka Dua ua hoʻolālā ʻo ia e hoʻohana i ka paepae noiʻi hou e hana i nā noiʻi hohonu me ka hoʻohana ʻana i nā hiʻohiʻona holoholona preclinical o ka maʻi kanesa āpau.
"ʻO nā haʻawina pharmacokinetic a me anticancer hou aku o nā nanodrugs berberine i nā hiʻohiʻona holoholona i vivo hiki ke hōʻike i kā lākou mau pono kūpono i ka mālama ʻana i ka maʻi kanesa a hoʻohuli iā lākou i mau ʻano hana therapeutic," wehewehe ʻo ia.
"I ka manawa a mākou i hōʻoia ai i ka mana anti-cancer o berberine nanodrugs i nā hiʻohiʻona holoholona preclinical, ʻo ka hana aʻe e neʻe i nā hoʻokolohua lapaʻau, a mākou e kamaʻilio nei me kekahi mau hui Sydney," wahi a Dr. Dua.
Eia kekahi, ua ʻōlelo ʻo Dr. Dua e pono e hōʻoia ʻia ka hiki o ka berberine e pale i ka hoʻi hou ʻana o ka maʻi kanesa: "ʻOiai ʻaʻole mākou i noiʻi i kēia, manaʻo mākou e aʻo iā ia i nā haʻawina e hiki mai ana, a ke manaʻoʻiʻo nei mākou e hōʻike ʻia nā berberine nanoforms. hana hoʻohiki. “.
Ua haʻi aku ʻo Kauka Osita Onuga, ke kaukaʻi thoracic a me ke kaukaʻi kōkua o ka ʻoki ʻoki ʻana ma St. John Cancer Institute ma Providence St. manaʻolana:
"He ʻāpana ʻo Berberine o ka lāʻau hikina, no laila ʻaʻole mākou e hoʻohana maʻamau i ka lāʻau lapaʻau o ke Komohana. Manaʻo wau he mea hoihoi ia no ka mea ke nānā nei mākou i nā mea a mākou i ʻike ai he mau pōmaikaʻi no ka lāʻau lapaʻau Hikina, a hoʻokomo i loko o ka noiʻi e kōkua i ka unuhi ʻana i ka lāʻau o ke Komohana. “.
"He hoʻohiki mau ia, akā aia i loko o ka lab, a ʻo ka nui o nā mea i loaʻa iā mākou ma ka lab ʻaʻole pono e alakaʻi i nā maʻi e mālama ʻia," wahi a Onuga. "Manaʻo wau ʻo ka mea aʻe e hana ai, ʻo ia ke hana i kekahi mau hoʻokolohua lapaʻau i nā mea maʻi a ʻike i ke ʻano."
ʻIke kekahi poʻe i nā hōʻailona maʻalahi o ka maʻi kanesa maʻi i ka wā mua o ka maʻi. E heluhelu no ka ʻike hou aku, me ka wā e ʻike ai i ke kauka.
Hiki mai ka ma'i 'a'ai ma nā 'ano like 'ole o nā wāhine a me nā kāne, akā like nā hō'ailona a me nā kumu pilikia. Maanei mākou e wehewehe ai i ka genetic a me ka hormonal ...
ʻO mākou kahi mea hana mea kanu lāʻau extract powder, hoʻokipa e hoʻouna i kāu mau nīnau e pili ana i kā mākou huahana a loaʻa iā mākou nā hoa hana kuleana e hoʻoponopono i kāu mau pilikia e pili ana i ke kūʻai mua a ma hope o ke kūʻai aku. Hoʻokaʻaʻike mai iā mākou i kēlā me kēia manawa!!!