Aia i loko o nā ʻili a me nā hua o nā hua waina a me nā huaʻai ka resveratrol, e hoʻolilo ana i ka waina ʻulaʻula i waiwai i kēia hui. Ua hōʻike ʻia e ka noiʻi he mau pono olakino maikaʻi kona, akā pono ʻoe e ʻike hou aʻe e pili ana i ka nui o ka mea hoʻohui āu e pono ai e lawe.
Inā ua lohe ʻoe e kōkua ana ka waina ʻulaʻula i ka hoʻohaʻahaʻa ʻana i ka cholesterol, a laila ua lohe paha ʻoe i ka resveratrol, kahi mea kanu i hoʻolaha nui ʻia i ka waina ʻulaʻula.
Akā ma waho aʻe o ka lilo ʻana i ʻāpana pono o ka waina ʻulaʻula a me nā meaʻai ʻē aʻe, loaʻa i ka resveratrol ka hiki ke olakino.
ʻO kaʻoiaʻiʻo, pili nā mea hoʻohui resveratrol me nā pono olakino kupaianaha he nui, me ka pale ʻana i ka hana o ka lolo a me ka hoʻohaʻahaʻa ʻana i ke koko (1, 2, 3, 4).
Hōʻike kēia ʻatikala i nā mea e pono ai ʻoe e ʻike e pili ana i ka resveratrol, me kāna mau pono olakino ʻehiku kiʻekiʻe loa.
He hui mea kanu ʻo Resveratrol e hana ana ma ke ʻano he antioxidant. ʻO nā kumu meaʻai nui e komo pū me ka waina ʻulaʻula, nā hua waina, kekahi mau hua, a me nā pīnati (5, 6).
Hoʻopili pinepine kēia hui i nā ʻili a me nā hua o nā hua waina a me nā hua. Pili kēia mau ʻāpana o ka hua waina i ka fermentation o ka waina ʻulaʻula a no laila he kiʻekiʻe loa ka nui o ka resveratrol (5, 7).
Eia nō naʻe, ua hana ʻia ka hapa nui o nā haʻawina resveratrol i nā holoholona a me nā ʻōmole hoʻāʻo e hoʻohana ana i nā nui o kēia hui (5, 8).
ʻO nā haʻawina palena i loko o ke kanaka, ua kālele ka hapa nui i nā ʻano i hoʻohui ʻia o ka hui, i loaʻa i nā ʻano kiʻekiʻe ma mua o nā mea i loaʻa mai ka meaʻai (5).
He hui antioxidant ʻo Resveratrol i loaʻa i ka waina ʻulaʻula, nā huaʻai a me nā pīnati. Ua hoʻohana nā haʻawina kanaka he nui i nā mea hoʻohui i loaʻa nā pae kiʻekiʻe o ka resveratrol.
Ma muli o kona mau waiwai antioxidant, hiki i ka resveratrol ke lilo i mea hoʻohui hoʻohiki no ka hoʻohaʻahaʻa ʻana i ke koko (9).
Ua hoʻoholo kahi loiloi 2015 e hiki i nā lāʻau kiʻekiʻe ke kōkua i ka hōʻemi ʻana i ke kaumaha ma nā paia o ke aʻa ke kuʻi ka puʻuwai (3).
Ua kapa ʻia kēia kaomi ʻo ke koko systolic a ʻike ʻia ʻo ia ka helu kiʻekiʻe ma ka heluhelu ʻana i ke koko.
ʻO ka maʻamau, piʻi aʻe ke koko systolic me ka ʻelemakule ma muli o ka atherosclerosis. Ke kiʻekiʻe ia, he mea ia e pilikia ai no nā maʻi cardiovascular.
Hiki iā Resveratrol ke hoʻokō i nā hopena hoʻohaʻahaʻa koko ma ke kōkua ʻana i ka hana ʻana i ka nitric oxide hou aʻe, kahi e hoʻomaha ai nā kīʻaha koko (10, 11).
Eia nō naʻe, ua ʻōlelo nā mea kākau o ka noiʻi e pono hou aku ka noiʻi e hana i nā ʻōlelo aʻoaʻo kikoʻī e pili ana i ka nui kūpono o ka resveratrol no nā hopena kiʻekiʻe loa ma ke koko.
Ua hōʻike ʻia kekahi mau haʻawina holoholona e hiki i nā mea hoʻohui resveratrol ke hoʻololi i nā lipids koko ma nā ʻano olakino (12, 13).
I loko o kahi noiʻi i ka makahiki 2016, ua hānai ʻia nā ʻiole i kahi meaʻai kiʻekiʻe i ka protein a me ka momona polyunsaturated i hoʻohui ʻia me ka resveratrol.
Ua ʻike nā kānaka noiʻi ua emi ka awelika o ka pae cholesterol holoʻokoʻa a me ke kaumaha o ke kino o nā ʻiole, ʻoiai ua piʻi ka pae o ka cholesterol "maikaʻi" HDL (13).
Me he mea lā e hoʻopilikia ana ʻo Resveratrol i nā pae cholesterol ma ka hoʻemi ʻana i ka hana o nā enzymes e kāohi ana i ka hana cholesterol (13).
Ma ke ʻano he antioxidant, hoʻemi pū ia i ka oxidation o ka cholesterol LDL "maikaʻi ʻole". ʻO ka oxidation o LDL ke alakaʻi i ka hoʻokumu ʻana o ka plaque i loko o ka paia arterial (9, 14).
Ma hope o ʻeono mahina o ka lāʻau lapaʻau, ua ʻike nā mea komo i lawe i ka ʻāpana hua waina ʻaʻole i hoʻopaʻa ʻia a i ʻole placebo i ka emi ʻana o 4.5% ma LDL a me ka emi ʻana o 20% ma LDL oxidized (15).
Hiki i nā mea hoʻohui Resveratrol ke hoʻomaikaʻi i nā pae lipid koko i nā holoholona. Ma ke ʻano he antioxidant, hoʻemi pū lākou i ka oxidation o ka LDL cholesterol.
Ua lilo ka hiki o ka hui ke hoʻolōʻihi i ke ola o nā meaola like ʻole i wahi nui o ka noiʻi (16).
Aia nā hōʻike e hoʻāla ana ka resveratrol i kekahi mau genes, no laila e pale ana i nā maʻi o ka ʻelemakule (17).
Hana like kēia me ke kāohi ʻana i ka calorie, kahi i hōʻike i nā hopena hoʻohiki i ka hoʻonui ʻana i ke ola ma o ka hoʻololi ʻana i ke ʻano o ka hōʻike ʻana o nā genes (18, 19).
Ua ʻike ʻia kahi loiloi o nā haʻawina e nānā ana i kēia loulou ua hoʻolōʻihi ka resveratrol i ke ola ma 60% o nā meaola i aʻo ʻia, akā ʻoi aku ka nui o ka hopena i nā meaola i pili ʻole i nā kānaka, e like me nā ilo a me nā iʻa (20).
Ua hōʻike ʻia nā haʻawina holoholona e hiki i nā mea hoʻohui resveratrol ke hoʻolōʻihi i ke ola. Eia nō naʻe, ʻaʻole maopopo inā e loaʻa iā lākou ka hopena like i nā kānaka.
Ua hōʻike ʻia kekahi mau noiʻi e hiki i ka inu ʻana i ka waina ʻulaʻula ke kōkua i ka lohi o ka emi ʻana o ka noʻonoʻo e pili ana i ka makahiki (21, 22, 23, 24).
Me he mea lā ke hoʻopilikia nei ia i nā ʻāpana protein i kapa ʻia ʻo amyloid beta, he mea koʻikoʻi ia i ke kūkulu ʻia ʻana o nā plaques hiʻona o ka maʻi Alzheimer (21, 25).
ʻOiai he mea hoihoi kēia noiʻi, he mau nīnau nō naʻe ko nā kānaka ʻepekema e pili ana i ka hiki o ke kino ke hoʻohana i ka resveratrol keu, e kaupalena ana i kona hoʻohana koke ʻana ma ke ʻano he mea hoʻohui pale lolo (1, 2).
He antioxidant ikaika ʻo Resveratrol a me ka hui anti-inflammatory e pale ai i nā hunaola o ka lolo mai ka hōʻino ʻia.
ʻO kēia mau pono e pili ana i ka hoʻomaikaʻi ʻana i ka ʻike o ka insulin a me ka pale ʻana i nā pilikia maʻi diabetes (26,27,28,29).
ʻO kahi wehewehe no ke ʻano o ka hana a ka resveratrol, hiki iā ia ke pale i kahi enzyme mai ka hoʻololi ʻana i ka glucose i sorbitol, kahi waiʻona kō.
Ke hōʻiliʻili nui ka sorbitol i loko o ke kino o ka poʻe me ka maʻi diabetes, hiki iā ia ke hana i ka oxidative stress e hōʻino ana i nā cell (30, 31).
Hiki paha i ka Resveratrol ke pōmaikaʻi nui aku i ka poʻe maʻi diabetes ma mua o ka poʻe ʻaʻole maʻi diabetes. Ma kekahi noiʻi holoholona, ​​ua ʻike ʻia ka waina ʻulaʻula a me ka resveratrol he mau antioxidants ikaika loa i nā ʻiole maʻi diabetes ma mua o nā ʻiole nondiabetic (32).
Ua ʻōlelo nā kānaka noiʻi hiki ke hoʻohana ʻia ka hui e mālama i ka maʻi diabetes a me kona mau pilikia i ka wā e hiki mai ana, akā pono hou aku ka noiʻi.
Kōkua ʻo Resveratrol i nā ʻiole e hoʻomaikaʻi i ka ʻike o ka insulin a hakakā i nā pilikia o ka maʻi diabetes. I ka wā e hiki mai ana, hiki i nā poʻe maʻi me ka maʻi diabetes ke pōmaikaʻi mai ka lāʻau lapaʻau resveratrol.
Ke aʻo ʻia nei nā mea hoʻohui lāʻau lapaʻau ma ke ʻano he ala e mālama ai a pale aku i ka ʻeha o nā hono. Ke lawe ʻia ma ke ʻano he mea hoʻohui, hiki i ka resveratrol ke kōkua i ka pale ʻana i ke cartilage mai ka haki ʻana (33, 34).
Ua hoʻokomo kekahi noiʻi i ka resveratrol i loko o nā hui kuli o nā lāpaki arthritic a ua ʻike ʻia he emi iki ka hōʻino ʻana o kēia mau lāpaki i ke cartilage (34).
Ua hōʻike ʻia nā haʻawina hoʻāʻo ʻē aʻe a me nā holoholona i ka hiki o kēia hui ke hōʻemi i ka mumū a pale i ka hōʻino ʻana o nā hono (33, 35, 36, 37).
Ua aʻo ʻia ʻo Resveratrol no kona hiki ke pale a mālama i ka maʻi kanesa, ʻoi aku hoʻi i loko o nā ʻōmole hoʻāʻo. Eia nō naʻe, ua hui pū ʻia nā hopena (30, 38, 39).
Ua hōʻike ʻia e hakakā i nā ʻano maʻi kanesa like ʻole i nā haʻawina holoholona a me nā ʻōmole hoʻāʻo, me ka ʻōpū, colon, ʻili, umauma, a me nā maʻi kanesa prostate (40, 41, 42, 43, 44).
Eia nō naʻe, ʻoiai ua mālama ʻia nā haʻawina a hiki i kēia lā i loko o nā ʻōmole hoʻāʻo a me nā holoholona, ​​​​pono ka noiʻi hou aku e hoʻomaopopo inā a pehea e hiki ai ke hoʻohana ʻia kēia hui e mālama i ka maʻi kanesa i loko o ke kanaka.
ʻAʻole i loaʻa i nā haʻawina e hoʻohana ana i nā mea hoʻohui resveratrol nā pilikia koʻikoʻi. Me he mea lā ua ʻae maikaʻi ʻia lākou e ka poʻe olakino (47).
Eia nō naʻe, pono e hoʻomaopopo ʻia i kēia manawa ʻaʻohe ʻōlelo aʻoaʻo paʻa e pili ana i ka nui o ka resveratrol e pono ai i ke kanaka ke lawe e loaʻa ai nā pono olakino.
Aia kekahi mau ʻōlelo aʻo, ʻoiai e pili ana i ka pili ʻana o ka resveratrol me nā lāʻau lapaʻau ʻē aʻe.
No ka mea, ua hōʻike ʻia nā lāʻau kiʻekiʻe e pale i ke kāpili ʻana o ke koko i loko o nā ʻōmole hoʻāʻo, hiki iā lākou ke hoʻonui i ke kahe koko a i ʻole ka ʻeha ke lawe ʻia me nā anticoagulants e like me heparin a warfarin paha, a i ʻole kekahi mau lāʻau ʻeha (48, 49).
Hoʻopaʻa pū ʻo Resveratrol i nā enzymes e kōkua i ka wehe ʻana i kekahi mau hui mai ke kino. ʻO ke ʻano kēia, hiki i kekahi mau lāʻau lapaʻau ke hōʻea i nā pae palekana ʻole. ʻO kēia kekahi mau lāʻau hoʻohaʻahaʻa koko, nā lāʻau anti-anxiety, a me nā immunosuppressants (50).
Inā ʻoe e lawe nei i ka lāʻau lapaʻau, makemake paha ʻoe e kamaʻilio me kāu kauka ma mua o ka lawe ʻana i ka resveratrol.