Aia ka resveratrol i loko o nā ʻili a me nā ʻanoʻano o nā hua waina a me nā hua, e waiwai ana ka waina ʻulaʻula i kēia pūhui. Hōʻike ka noiʻi he nui nā pono olakino, akā pono ʻoe e ʻike hou aʻe e pili ana i ka nui o nā mea hoʻohui e pono ai ʻoe e lawe.
Inā ua lohe ʻoe ua kōkua ka waina ʻulaʻula e hoʻohaʻahaʻa i ka cholesterol, a laila ua lohe paha ʻoe i ka resveratrol, kahi mea kanu i hoʻohui ʻia i ka waina ʻulaʻula.
Akā ma kahi o ka lilo ʻana i mea pono o ka waina ʻulaʻula a me nā meaʻai ʻē aʻe, hiki i ka resveratrol ke olakino.
ʻO ka ʻoiaʻiʻo, pili nā mea hoʻohui resveratrol me nā pōmaikaʻi olakino he nui, me ka pale ʻana i ka hana o ka lolo a me ka hoʻohaʻahaʻa ʻana i ke koko (1, 2, 3, 4).
Ua wehewehe kēia ʻatikala i nā mea e pono ai ʻoe e ʻike e pili ana i ka resveratrol, me kāna mau pono olakino maikaʻi loa ʻehiku.
ʻO Resveratrol kahi pūhui mea kanu e hana ana ma ke ʻano he antioxidant. ʻO nā kumu meaʻai nui ka waina ʻulaʻula, nā hua waina, kekahi mau hua, a me nā pīni (5, 6).
Hoʻopili kēia hui i nā ʻili a me nā hua o nā hua waina a me nā hua. Aia kēia mau ʻāpana o ka hua waina i ka fermentation o ka waina ʻulaʻula a no laila ke kiʻekiʻe kiʻekiʻe o ka resveratrol (5, 7).
Eia naʻe, ua hana ʻia ka hapa nui o nā haʻawina resveratrol i nā holoholona a me nā paipu hoʻāʻo me ka hoʻohana ʻana i ka nui o kēia pūhui (5, 8).
ʻO nā haʻawina liʻiliʻi i loko o ke kanaka, ua nānā ka hapa nui i nā ʻano i hoʻohui ʻia o ka pūhui, i loaʻa i nā ʻano kiʻekiʻe ma mua o nā mea i loaʻa mai ka meaʻai (5).
ʻO Resveratrol kahi pūhui antioxidant i loaʻa i loko o ka waina ʻulaʻula, nā hua a me nā pī. Nui nā haʻawina kanaka i hoʻohana i nā mea hoʻohui i loaʻa nā pae kiʻekiʻe o resveratrol.
Ma muli o kāna mau waiwai antioxidant, hiki i ka resveratrol ke lilo i kumu hoʻohiki no ka hoʻohaʻahaʻa ʻana i ke koko (9).
Ua hoʻoholo ka loiloi 2015 e hiki ke kōkua i nā koina kiʻekiʻe e hōʻemi i ke koʻikoʻi ma nā paia o ke aʻa ke kuʻi ka naʻau (3).
Kapa ʻia kēia kaomi ʻana i ke koko systolic a ʻike ʻia ʻo ia ka helu kiʻekiʻe o ka heluhelu ʻana i ke koko.
Hoʻonui pinepine ʻia ke koko systolic me ka makahiki ma muli o ke atherosclerosis. Ke kiʻekiʻe, he kumu pilikia ia no ka maʻi cardiovascular.
Hiki i ka Resveratrol ke hoʻokō i nā hopena hoʻohaʻahaʻa i ke koko ma o ke kōkua ʻana i ka hana ʻana i ka nitric oxide, kahi e hoʻomaha ai nā kīʻaha koko (10, 11).
Eia nō naʻe, ua ʻōlelo nā mea kākau noiʻi e pono ai ka noiʻi hou e hana i nā ʻōlelo aʻoaʻo kikoʻī e pili ana i ka nui o ka resveratrol no nā hopena kiʻekiʻe ma ke kahe koko.
Ua hōʻike ʻia kekahi mau noiʻi holoholona e hiki i nā mea hoʻohui resveratrol ke hoʻololi i nā lipids koko i nā ala olakino (12, 13).
Ma kahi noiʻi 2016, ua hānai ʻia nā ʻiole i kahi meaʻai kiʻekiʻe i ka protein a me ka momona polyunsaturated i hoʻohui ʻia me ka resveratrol.
Ua ʻike ka poʻe noiʻi i ka emi ʻana o ka nui o ka cholesterol a me ke kaumaha o ke kino o nā ʻiole, aʻo ka piʻi ʻana o ka "maikaʻi" HDL cholesterol (13).
ʻIke ʻia ʻo Resveratrol e hoʻopilikia i nā pae cholesterol ma ka hoʻohaʻahaʻa ʻana i ka hana o nā enzymes e hoʻomalu i ka hana cholesterol (13).
Ma ke ʻano he antioxidant, hoʻemi ia i ka oxidation o "kino" LDL cholesterol. ʻO ka oxidation o LDL ke alakaʻi i ka hoʻokumu ʻana o ka plaque ma ka paia arterial (9, 14).
Ma hope o ʻeono mahina o ka mālama ʻana, ua loaʻa i nā poʻe e lawe ana i ka hua waina non-concentrated a i ʻole kahi placebo i kahi hōʻemi 4.5% o ka LDL a me 20% hoʻemi i ka LDL oxidized (15).
Hiki i nā mea hoʻohui Resveratrol ke hoʻomaikaʻi i nā pae lipid koko i nā holoholona. Ma ke ʻano he antioxidant, hoʻemi lākou i ka oxidation o LDL cholesterol.
ʻO ka hiki i ka pūhui ke hoʻonui i ke ola o nā mea ola like ʻole i lilo i wahi nui o ka noiʻi (16).
Aia kekahi mau hōʻike e hoʻāla ai ka resveratrol i kekahi mau genes, a laila pale i nā maʻi o ka ʻelemakule (17).
Hana like kēia me ka palena o ka calorie, kahi i hōʻike i nā hopena hoʻohiki i ka hoʻonui ʻana i ke ola ma o ka hoʻololi ʻana i ke ʻano o ka hōʻike ʻana o nā genes (18, 19).
ʻO ka loiloi o nā haʻawina e nānā ana i kēia loulou ua ʻike ʻia ua hoʻolōʻihi ʻia ka resveratrol i ke ola ma 60% o nā mea ola i aʻo ʻia, akā ua ʻike nui ʻia ka hopena i nā meaola pili ʻole i ke kanaka, e like me nā ilo a me nā iʻa (20).
Ua hōʻike ʻia nā haʻawina holoholona e hiki i nā mea hoʻohui resveratrol ke hoʻonui i ke ola. Akā naʻe, ʻaʻole maopopo inā loaʻa iā lākou ka hopena like i ke kanaka.
Ua hōʻike ʻia kekahi mau haʻawina e hiki ke kōkua i ka inu ʻana i ka waina ʻulaʻula i ka emi ʻana o ka cognitive pili i ka makahiki (21, 22, 23, 24).
ʻIke ʻia e keʻakeʻa i nā ʻāpana protein i kapa ʻia ʻo amyloid beta, he mea koʻikoʻi i ka hoʻokumu ʻana i nā ʻano plaques o ka maʻi Alzheimer (21, 25).
ʻOiai he mea hoihoi kēia noiʻi ʻana, he mau nīnau ka poʻe ʻepekema e pili ana i ka hiki o ke kino ke hoʻohana i ka resveratrol hou, e kaupalena ana i kona hoʻohana koke ʻana ma ke ʻano he mea hoʻohui pale pale lolo (1, 2).
ʻO Resveratrol kahi pūhui antioxidant ikaika a me ka anti-inflammatory i hiki ke pale aku i nā pūpū lolo mai ka pōʻino.
ʻO kēia mau pōmaikaʻi e pili ana i ka hoʻomaikaʻi ʻana i ka insulin sensitivity a me ka pale ʻana i nā pilikia maʻi diabetes (26,27,28,29).
ʻO kahi wehewehe no ka hana ʻana o ka resveratrol ʻo ia ka hiki ke pale i kahi enzyme mai ka hoʻololi ʻana i ka glucose i sorbitol, kahi waiʻona kō.
Ke hōʻiliʻili ʻia ka sorbitol i loko o ke kino o ka poʻe me ka maʻi maʻi diabetes, hiki iā ia ke hoʻoulu i ke koʻikoʻi oxidative e hōʻino ana i nā cell (30, 31).
Hiki paha i ka Resveratrol ke pōmaikaʻi i ka poʻe maʻi maʻi ma mua o ka poʻe maʻi ʻole. I loko o kahi noiʻi holoholona, ​​ua ʻike ʻia ka waina ʻulaʻula a me ka resveratrol i ʻoi aku ka ikaika o nā antioxidants i nā mice diabetic ma mua o nā mice nondiabetic (32).
Ua ʻōlelo ka poʻe noiʻi hiki ke hoʻohana ʻia ka pūhui no ka mālama ʻana i ka maʻi diabetes a me kona mau pilikia i ka wā e hiki mai ana, akā pono ka noiʻi hou aku.
Kōkua ʻo Resveratrol i nā ʻiole e hoʻomaikaʻi i ka naʻau o ka insulin a hakakā i nā pilikia maʻi diabetes. I ka wā e hiki mai ana, hiki i nā poʻe maʻi me ka maʻi maʻi ke loaʻa ka pōmaikaʻi mai ka lāʻau resveratrol.
Ke aʻo ʻia nei nā mea hoʻohui lāʻau ma ke ʻano he ala e mālama ai a pale aku i ka ʻeha hui. Ke lawe ʻia i mea hoʻohui, hiki i ka resveratrol ke kōkua i ka pale ʻana i ka cartilage mai ka haki ʻana (33, 34).
Hoʻokahi haʻawina i hoʻokomo i ka resveratrol i loko o nā ami kuli o nā lapeti maʻi a ʻike ʻia ua emi ka pōʻino o ka cartilage o kēia mau lākeke (34).
Ua hōʻike ʻia nā haʻawina hoʻāʻo ʻē aʻe a me nā haʻawina holoholona i ka hiki o kēia pūhui ke hōʻemi i ka mumū a pale i ka pōʻino hui (33, 35, 36, 37).
Ua aʻo ʻia ʻo Resveratrol no kona hiki ke pale a mālama i ka maʻi kanesa, ʻoi aku hoʻi i nā paipu hoʻāʻo. Eia naʻe, ua hui pū ʻia nā hopena (30, 38, 39).
Ua hōʻike ʻia i ka hakakā ʻana i nā ʻano maʻi maʻi maʻi i loko o nā haʻawina holoholona a me ka hoʻāʻo ʻana, e like me ka ʻōpū, ka ʻōpū, ka ʻili, ka umauma, a me nā maʻi maʻi prostate (40, 41, 42, 43, 44).
Eia nō naʻe, ʻoiai ua mālama ʻia nā haʻawina a hiki i kēia lā i loko o nā paipu hoʻāʻo a me nā holoholona, ​​​​pono e noiʻi hou aku e hoʻomaopopo inā a pehea e hoʻohana ʻia ai kēia pūhui e mālama i ka maʻi kanesa i loko o ke kanaka.
ʻAʻole i loaʻa i nā haʻawina e hoʻohana ana i nā mea hoʻohui resveratrol he pilikia nui. ʻIke ʻia lākou e ʻae maikaʻi ʻia e ka poʻe olakino (47).
Eia naʻe, pono e hoʻomaopopo ʻia aia i kēia manawa ka nele o nā ʻōlelo aʻoaʻo e pili ana i ka nui o ka resveratrol e lawe ai ke kanaka e loaʻa ai nā pono olakino.
Aia kekahi mau ʻōlelo aʻo, e pili ana i ka pili ʻana o resveratrol me nā lāʻau lapaʻau ʻē aʻe.
Ma muli o ka hōʻike ʻia ʻana o ka nui o ka nui e pale i ke koko koko i loko o nā paipu hoʻāʻo, hiki iā lākou ke hoʻonui i ke koko a i ʻole ka ʻeha ke lawe ʻia me nā anticoagulants e like me ka heparin a i ʻole warfarin, a i ʻole kekahi mau lāʻau ʻeha (48, 49).
Hoʻopaʻa pū ʻo Resveratrol i nā enzyme e kōkua i ka wehe ʻana i kekahi mau pūhui mai ke kino. 'O ia ho'i, hiki i kekahi mau lā'au lapa'au ke pi'i i nā pae palekana. ʻO kēia kekahi mau lāʻau hoʻohaʻahaʻa i ke koko, nā lāʻau anti-anxiety, a me nā immunosuppressants (50).
Inā ʻoe e lawe nei i ka lāʻau lapaʻau, makemake paha ʻoe e kamaʻilio me kāu kauka ma mua o ka lawe ʻana i ka resveratrol.