ʻO Berberine, a i ʻole berberine hydrochloride, kahi hui i loaʻa i nā mea kanu he nui. Hiki iā ia ke kōkua i ka mālama ʻana i nā maʻi e like me ka maʻi diabetes, ka cholesterol kiʻekiʻe a me ke koko kiʻekiʻe. Eia nō naʻe, hiki i nā hopena ʻaoʻao ke komo pū me ka ʻōpū ʻeha a me ka nausea.
Ua lilo ʻo Berberine i ʻāpana o ka lāʻau lapaʻau kuʻuna Kina a me Ayurvedic no nā tausani makahiki. Hana ia i loko o ke kino ma nā ʻano like ʻole a hiki ke hoʻololi i loko o nā hunaola o ke kino.
Ua hōʻike ʻia ma ka noiʻi ʻana ma luna o ka berberine e hiki iā ia ke mālama i nā ʻano maʻi metabolic like ʻole, me ka maʻi diabetes, ka momona, a me nā maʻi puʻuwai. Hiki nō hoʻi iā ia ke hoʻomaikaʻi i ke olakino o ka ʻōpū.
ʻOiai ke ʻano palekana o ka berberine a he liʻiliʻi nā hopena ʻaoʻao, pono ʻoe e nīnau i kāu kauka ma mua o ka lawe ʻana.
He mea antibacterial maikaʻi paha ʻo Berberine. Ua ʻike ʻia kahi noiʻi 2022 e kōkua ana ka berberine i ka pale ʻana i ka ulu ʻana o Staphylococcus aureus.
Ua ʻike ʻia kekahi noiʻi ʻē aʻe hiki i ka berberine ke hōʻino i ka DNA a me nā protein o kekahi mau bacteria.
Hōʻike nā noiʻi he waiwai anti-inflammatory ka berberine, ʻo ia hoʻi ke kōkua i ka mālama ʻana i ka maʻi diabetes a me nā maʻi ʻē aʻe e pili ana me ka mumū.
Ua hōʻike ʻia e ka noiʻi he pono paha ka berberine i ka mālama ʻana i ka maʻi diabetes. Ua hōʻike ʻia e ka noiʻi hiki iā ia ke loaʻa ka hopena maikaʻi ma:
Ua ʻike ʻia ka loiloi like ʻana ua ʻoi aku ka maikaʻi o ka hui pū ʻana o ka berberine a me kahi lāʻau hoʻohaʻahaʻa kō koko ma mua o kēlā me kēia lāʻau lapaʻau wale nō.
Wahi a kahi noiʻi i ka makahiki 2014, hōʻike ka berberine i ka hoʻohiki ʻana he lāʻau lapaʻau kūpono no ka maʻi diabetes, ʻoiai no ka poʻe hiki ʻole ke lawe i nā lāʻau antidiabetic e kū nei ma muli o ka maʻi puʻuwai, ka hāʻule ʻana o ke ake, a i ʻole nā ​​​​pilikia puʻupaʻa.
Ua ʻike ʻia kekahi loiloi o nā palapala i hui pū ʻia me ka berberine me nā loli o ke ʻano o ka noho ʻana i hoʻemi i nā pae kō koko ma mua o nā loli o ke ʻano o ka noho ʻana wale nō.
Me he mea lā e hoʻāla ana ʻo Berberine i ka protein kinase i hoʻāla ʻia e ka AMP, kahi e kōkua ai i ka hoʻoponopono ʻana i ka hoʻohana ʻana o ke kino i ke kō koko. Manaʻo nā kānaka noiʻi e hiki i kēia hoʻāla ʻana ke kōkua i ka mālama ʻana i ka maʻi diabetes a me nā pilikia olakino e pili ana e like me ka momona a me ka cholesterol kiʻekiʻe.
Ua hōʻike kekahi meta-analysis ʻē aʻe o 2020 i nā hoʻomaikaʻi ʻana i ke kaumaha o ke kino a me nā ʻano metabolic me ka ʻole o ka hoʻonui nui ʻana i ka hana enzyme ate.
Eia nō naʻe, pono nā kānaka ʻepekema e hana i nā haʻawina nui a pālua makapō e hoʻoholo piha i ka palekana a me ka pono o ka berberine.
E kamaʻilio me kāu kauka ma mua o ka lawe ʻana i ka berberine no ka maʻi diabetes. ʻAʻole paha ia e kūpono no nā mea āpau a hiki ke launa pū me nā lāʻau lapaʻau ʻē aʻe.
Hiki i nā pae kiʻekiʻe o ka cholesterol a me ka lipoprotein haʻahaʻa (LDL) triglycerides ke hoʻonui i ka pilikia o ka maʻi puʻuwai a me ka hahau.
Hōʻike kekahi mau hōʻike e hiki i ka berberine ke kōkua i ka hoʻohaʻahaʻa ʻana i ka cholesterol LDL a me nā triglycerides. Wahi a kekahi loiloi, hōʻike nā haʻawina holoholona a me ke kanaka e hoʻohaʻahaʻa ana ka berberine i ka cholesterol.
Hiki i kēia ke kōkua i ka hoʻohaʻahaʻa ʻana i ka LDL, ka cholesterol "maikaʻi ʻole", a hoʻonui i ka HDL, ka cholesterol "maikaʻi".
Ua ʻike ʻia kahi loiloi o nā palapala i hui pū ʻia me ka berberine me nā loli o ke ʻano o ka nohona he ʻoi aku ka maikaʻi o ka mālama ʻana i ka cholesterol kiʻekiʻe ma mua o nā loli o ke ʻano o ka nohona wale nō.
Manaʻo nā kānaka noiʻi e hana like paha ka berberine me nā lāʻau hoʻohaʻahaʻa cholesterol me ka ʻole o ka hopena like.
Ua ʻike ʻia kahi loiloi o nā palapala i ʻoi aku ka maikaʻi o ka berberine i ka hui pū ʻana me nā lāʻau hoʻohaʻahaʻa koko ma mua o kāna iho.
Eia kekahi, hōʻike nā hopena mai nā haʻawina ʻiole e hiki i ka berberine ke hoʻopaneʻe i ka hoʻomaka ʻana o ke koko kiʻekiʻe a kōkua i ka hōʻemi ʻana i kona koʻikoʻi ke kū mai ke koko kiʻekiʻe.
Ua hōʻike ʻia kekahi loiloi i ka pohō kaumaha nui i nā poʻe e lawe ana i 750 milligrams (mg) o barberry ʻelua i ka lā no 3 mau mahina. He mea kanu ʻo Barberry i loaʻa ka nui o ka berberine.
Eia kekahi, ua ʻike ʻia kahi noiʻi pālua makapō i ka poʻe me ka metabolic syndrome i lawe i 200 mg o barberry ʻekolu manawa i ka lā he haʻahaʻa ka nui o ke kino.
Ua ʻike ʻia e kahi hui e hana ana i kahi noiʻi ʻē aʻe e hiki i ka berberine ke hoʻoulu i ka ʻiʻo adipose brown. Kōkua kēia ʻiʻo i ke kino e hoʻololi i ka meaʻai i ka wela o ke kino, a ʻo ka hoʻonui ʻia ʻana o ka hoʻoulu ʻana e kōkua i ka mālama ʻana i ka momona a me ka metabolic syndrome.
Hōʻike kekahi mau noiʻi e hana like ana ka berberine me ka lāʻau metformin, ka mea a nā kauka e kuhikuhi pinepine ai e mālama i ka maʻi diabetes type 2. ʻO ka ʻoiaʻiʻo, hiki i ka berberine ke hoʻololi i nā bacteria o ka ʻōpū, hiki ke kōkua i ka mālama ʻana i ka momona a me ka maʻi diabetes.
ʻO ka maʻi polycystic ovary (PCOS) ke loaʻa i nā wahine nā pae kiʻekiʻe o kekahi mau hormones kāne. ʻO ka maʻi he hormonal a me ka metabolic imbalance e hiki ai ke alakaʻi i ka hānau ʻole ʻana a me nā pilikia olakino ʻē aʻe.
Hoʻopili ʻia ka maʻi ovary polycystic me nā pilikia he nui e hiki ai i ka berberine ke kōkua i ka hoʻoponopono. Eia kekahi laʻana, hiki i ka poʻe me PCOS ke loaʻa pū kekahi:
I kekahi manawa, kuhikuhi nā kauka i ka metformin, kahi lāʻau lapaʻau maʻi diabetes, e mālama i ka PCOS. ʻOiai he like nā hopena o ka berberine me ka metformin, he koho lapaʻau maikaʻi paha ia no ka PCOS.
Ua ʻike ʻia kahi loiloi ʻōnaehana he mea hoʻohiki ka berberine i ka mālama ʻana i ka polycystic ovary syndrome me ke kūʻē ʻana o ka insulin. Eia nō naʻe, ua ʻōlelo nā mea kākau e pono ana ka noiʻi hou aku no ka hōʻoia ʻana o kēia mau hopena.
Hiki i ka Berberine ke hoʻololi i nā molekala pūnaewele, hiki ke loaʻa kahi pōmaikaʻi ʻē aʻe: ke kaua ʻana i ka maʻi kanesa.
Hōʻike kekahi haʻawina ʻē aʻe e kōkua ana ka berberine i ka mālama ʻana i ka maʻi kanesa ma ke kāohi ʻana i kona holomua a me ke ola maʻamau. Hiki iā ia ke pāʻani i kahi kuleana i ka pepehi ʻana i nā hunaola kanesa.
Ma muli o kēia ʻikepili, ʻōlelo nā mea kākau he "lāʻau lapaʻau anticancer" kūpono loa, palekana, a kūpono hoʻi ke kumukūʻai ʻo berberine.
Eia nō naʻe, he mea nui e hoʻomanaʻo ua aʻo wale nā ​​​​​​mea noiʻi i nā hopena o ka berberine ma nā ʻōpū kanesa ma ka hale hana a ʻaʻole i loko o ke kanaka.
Wahi a kekahi mau noiʻi i paʻi ʻia i ka makahiki 2020, inā hiki i ka berberine ke kōkua i ka mālama ʻana i ke kanesa, ka mumū, ka maʻi diabetes a me nā maʻi ʻē aʻe, ma muli paha o kona hopena maikaʻi i ka microbiome gut. Ua ʻike nā kānaka ʻepekema i kahi pilina ma waena o ka microbiome gut (nā kolone o nā bacteria i loko o nā ʻōpū) a me kēia mau kūlana.
Loaʻa iā Berberine nā waiwai antibacterial a hoʻopau i nā bacteria ʻino mai nā ʻōpū, no laila e paipai ana i ka ulu ʻana o nā bacteria olakino.
ʻOiai nā haʻawina i loko o ke kanaka a me nā rodents e hōʻike ana he ʻoiaʻiʻo paha kēia, ua ʻōlelo ka poʻe ʻepekema e pono ana ka noiʻi hou aku e hōʻoia i ka hopena o ka berberine i nā kānaka a inā palekana ke hoʻohana.
Ua ʻōlelo ka ʻAhahui ʻAmelika o nā Kauka Naturopathic (AANP) e loaʻa ana nā mea hoʻopihapiha berberine ma ke ʻano hoʻopihapiha a i ʻole ka capsule.
Hoʻohui lākou he nui nā haʻawina e paipai ana i ka lawe ʻana i 900-1500 mg i kēlā me kēia lā, akā ʻo ka hapa nui o ka poʻe e lawe i 500 mg ʻekolu manawa i ka lā. Eia nō naʻe, koi ka AANP i nā kānaka e nīnau i ke kauka ma mua o ka lawe ʻana i ka berberine e nānā inā palekana ke hoʻohana a i ka nui o ka lāʻau e hiki ai ke lawe ʻia.
Inā ʻae kekahi kauka ua palekana ka hoʻohana ʻana i ka berberine, pono e nānā ka poʻe i ka lepili huahana no ka hōʻoia ʻaoʻao ʻekolu, e like me ka National Science Foundation (NSF) a i ʻole NSF International, wahi a AANP.
Ua ʻike nā mea kākau o kahi noiʻi 2018 ua ʻokoʻa loa ka nui o nā ʻano o nā capsules berberine like ʻole, kahi e alakaʻi ai i ka huikau e pili ana i ka palekana a me ka nui o ka lāʻau. ʻAʻole lākou i ʻike he hōʻike pono nā kumukūʻai kiʻekiʻe i ka maikaʻi o ka huahana.
ʻAʻole hoʻoponopono ka US Food and Drug Administration (FDA) i nā mea hoʻohui meaʻai. ʻAʻohe hōʻoia e palekana a maikaʻi paha nā mea hoʻohui, a ʻaʻole hiki ke hōʻoia i ka maikaʻi o ka huahana i nā manawa a pau.
Ua ʻōlelo nā kānaka ʻepekema he nui nā ʻano o ka berberine a me ka metformin a he mea pono paha nā mea ʻelua i ka mālama ʻana i ka maʻi diabetes type 2.
Eia nō naʻe, inā kuhikuhi ke kauka i ka metformin no ke kanaka, ʻaʻole lākou e noʻonoʻo i ka berberine ma ke ʻano he koho ʻē aʻe me ka ʻole o ka kūkākūkā mua ʻana me kā lākou kauka.
E kuhikuhi nā kauka i ka nui kūpono o ka metformin no ke kanaka ma muli o nā haʻawina lapaʻau. He mea hiki ʻole ke ʻike pehea ka kūlike o nā mea hoʻohui i kēia nui.
Hiki i ka Berberine ke launa pū me ka metformin a hoʻopilikia i kou kō koko, e paʻakikī ai ke kaohi. Ma kekahi noiʻi, ʻo ka lawe pū ʻana i ka berberine a me ka metformin i hōʻemi i nā hopena o ka metformin ma 25%.
Hiki paha iā Berberine ke lilo i koho kūpono i ka metformin no ka kaohi ʻana i ke kō koko i kekahi lā, akā pono hou aku ka noiʻi.
Ua ʻōlelo ke National Center for Complementary and Integrative Health (NCCIH) ʻaʻole paha e hoʻopilikia nui ka goldenrod, nona ka berberine, i ka wā pōkole inā lawe waha ʻia e nā pākeke. Eia nō naʻe, ʻaʻohe ʻike lawa e hōʻike ai he palekana ia no ka hoʻohana lōʻihi.
I nā haʻawina holoholona, ​​​​ua ʻike nā kānaka ʻepekema i nā hopena e pili ana i ke ʻano o ka holoholona, ​​​​ka nui a me ka lōʻihi o ka lawelawe ʻana:
He mea nui e kamaʻilio me kāu kauka ma mua o ka lawe ʻana i ka berberine a i ʻole nā ​​​​mea hoʻohui ʻē aʻe no ka mea ʻaʻole palekana lākou a ʻaʻole kūpono paha no nā mea āpau. ʻO kēlā me kēia mea i loaʻa i kahi hopena maʻi i kekahi huahana lāʻau lapaʻau e hoʻōki koke i ka hoʻohana ʻana.