1. Ka Abstract o Aframomum Melegueta

ʻO kaAframomum Melegueta, kamaaina no ʻApelika Komohana, loaʻa ka ʻala cardamom a me ka ʻono peppery. Ua hoʻohana nui ʻia ʻo ia ma ke ʻano he mea pani i ka wā i liʻiliʻi ai ka pepa ma ʻEulopa i ke kenekulia 13, a ua kapa ʻia ʻo ia ka "hua o ka lani" no ka mea ua manaʻo ʻia he lokomaikaʻi mai ka lani mai.

He mau inoa like ʻole ʻo Aframomum Melegueta e like me ka ʻai o ka paradaiso, ʻo Atare (ma Yoruba), chitta (Hausa), a i ʻole pepa Guinea, hoʻokahi hua me ka nui o ka mana hoʻōla a ʻo kona mau pōmaikaʻi i ke kanaka me he mea lā he pau ʻole.

Hoʻohana ʻia ʻo Aframomum melegueta (Grains of Paradise) no ka mālama ʻana i nā maʻi maʻi e like me nā maʻi urinary tract i hoʻokumu ʻia e Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, Staphylococcus saprophyticus, Proteus mirabilis, methicillinresistant Staphylococcus aureus, Shinella spp, a me Salmonella spp. Hōʻike ia i kekahi ʻōlelo hoʻohiki i ka hoʻomalu ʻana i ka momona-nui ma nā doses hiki ke hoʻopau ʻia i nā huahana meaʻai a me ka concoction lāʻau.

2. Wahi Hoʻolaha

Aframomum Melegueta（Paradise Pepper）, nona ka inoa maoli ʻo African Cardamom, i ʻike ʻia ʻo Peppercorn, Guinea Pepper, Melegueta Pepper, Paradise Pepper, a i ʻole Alligator Pepper, he lāʻau mau loa ia o ka ʻohana Zingiberaceae. He kanaka maoli no na kapakai o Aferika Komohana. Wehe ʻia nā pua poni, ʻano pū me nā pua, loaʻa nā hua 5-7 cm lōʻihi a loaʻa nā hua ʻulaʻula-ʻulaʻula. ʻO Peppery, no ka mea ua lilo ia i mea pani mua. I kēia manawa he mea maʻamau wale ia i ka ʻai kūloko ma ʻApelika. ʻO ia kekahi mea ʻala Silk Road i nalowale mai nā meaʻai Eurasia hou, akā hoʻohana mau ʻia ma nā wahi o ke Komohana a me ʻApelika ʻĀkau, a he mea waiwai nui i nā wahi o ʻAitiopa. ʻO ke kāleka ʻApelika, ka mea maoli i nā wahi kahakai o ʻApelika komohana, me he mea lā ua hoʻohana ʻia ma kahi kokoke i Ghana i kēia manawa i ka wā mua a ma hope mai ua hoʻouna ʻia i kekahi mau wahi awa ma ʻApelika hikina a i ʻole ma ke kahakai Mediterranean e kālepa ai ma ke alanui Silk. ʻO ka mea ʻala, ʻo ia ka mea i huhū nui ʻia i ka kuke ʻEulopa i ka wā o ka Renaissance mua, ua mae mālie mai ka papaʻaina i ka makahiki ʻumikumamāwalu a laila nalowale mai nā mākeke ʻEulopa, pani ʻia e ke kāleka a me nā mea ʻala ʻē aʻe i lawe ʻia mai Asia a puni ka honua.

3. Hoʻolauna o 6-Paradol

Ua ʻike ʻia ʻo Paradol, kahi metabolite non-pungent o shogaol e ka hoʻemi enzymatic, loaʻa nā hana anti-inflammatory. Hōʻike nā ʻike in vitro i kēia manawa i nā waiwai inhibitory o 6-paradol i ka mālama ʻana i ka neuroinflammation i ka microglia e pili ana i ka in vivo therapeutic potential for cerebral ischemia. ʻO 6-paradol ka neuroprotective efficacy i ka cerebral ischemia hiki ke hoʻohana ʻia i ka mālama ʻana i nā maʻi CNS ʻē aʻe kahi neuroinflammation kahi hiʻohiʻona pathological. Eia kekahi, inā hōʻike ʻia ka 6-paradol i nā maʻi CNS ʻē aʻe, ʻoi aku ka maikaʻi o kāna waiwai non-pungent i ka liʻiliʻi o nā hopena ʻaoʻao ma ka ʻōpū, ʻo ia hoʻi, hiki ke lawe ʻia i ka wā lōʻihi, ʻaʻole like me ka ginger a i ʻole nā mea pili. paha 6-shogaol.

6-paradolhe antimalarial ikaika loa a he mea nui oZoluaʻauʻau metabolite.

ʻO 6-Paradol (inoa IUPAC [1-(4-hydroxy-3-methoxyphenyl) decan-3-one]) he pūhui phenolic pungent i loaʻa i nā mea kanu o ka ʻohana Zingiberaceae, e like me ka ginger a me nā kīʻaha o ka paradaiso (Aframomum meleguetaaiʻole ka pepa alligator). E like me ka mea i ʻōlelo ʻia ma nā wahi ʻē aʻe, ua hōʻike kekahi mau haʻawina i ka antioxidant, anti-inflammatory, cytotoxic, anti-hyperlipidaemic, hypoglycaemic, a me nā hana antitumor o nā pūhui paradol like ʻole i nā ʻano holoholona like ʻole.