ʻO ka waika Arachidonic (ARA), ka ʻakika docosahexaenoic (DHA) a me ka ʻakika eicosapentaenoic (EPA) he mau ʻakika momona polyunsaturated lōʻihi (LCPUFA). Loaʻa ka Carotenoids, me ka lutein a me ka zeaxanthin (LZ), i loko o nā lau ʻōmaʻomaʻo.
He nui ka ARA a me DHA i ka lolo a he mau mea nui ia o ka phospholipids. Ua hōʻike nā haʻawina e hiki ke hoʻonui i ka hana hoʻomanaʻo i ka hoʻonui ʻana me DHA a me EPA kiʻekiʻe.
Eia kekahi, ua hōʻike ʻia ʻo LZ, kahi mea antioxidant o ka lolo, he hopena pale i nā pūnaewele nerve, a laila e hoʻopilikia ai i ka hana cognitive. Eia naʻe, ʻaʻole maopopo ka maikaʻi o ka lutein a me ka zeaxanthin i ka hana hoʻomanaʻo ma muli o nā hopena kū'ē mai nā haʻawina hana mua.
Ma muli o ka loaʻa ʻana o ARA, DHA, EPA, L a me Z (LCPUFA + LZ) i loko o ka lolo, a me kekahi mau hōʻike no ka hoʻomaikaʻi ʻana i ka hana hoʻomanaʻo, ua manaʻo nā mea kākau o kēia noiʻi e hiki ke hoʻomaikaʻi i ka hui ʻana o kēia mau mea. hoʻomanaʻo. hana ma ka lolo. ʻelemakule olakino.
Ua alakaʻi nā kānaka noiʻi Iapana i kahi 24-week, randomized, double-blind, placebo-controlled, parallel group study no ka hopena o LCPUFA + LH ma ka hana hoʻomanaʻo i nā poʻe ʻelemakule Kepani olakino me nā pilikia hoʻomanaʻo akā ʻaʻohe dementia.
ʻAʻole lākou i ʻike i nā ʻokoʻa nui ma waena o nā hui. Eia nō naʻe, i loko o kahi hōʻuluʻulu hui ʻana o kahi hui o nā mea komo me ka emi ʻana o ka cognitive, ua ʻike ʻia nā hoʻomaikaʻi nui.
Hoʻopau ka hōʻike: "Ke hōʻike nei kēia haʻawina no ka manawa mua e hiki i ka hui pū ʻana o LCPUFA a me LZ ke hoʻomaikaʻi i ka hana hoʻomanaʻo i nā poʻe ʻelemakule olakino Iapana me ka emi ʻana o ka cognitive akā ʻaʻohe dementia." 'kikokikona ad1′); });
ʻO ka huina o 120 mau mea komo mai Tokyo a me nā wahi a puni i hoʻokaʻawale ʻia i ʻekolu pūʻulu: (1) hui placebo e loaʻa ana i kahi placebo ma ke ʻano he meaʻai meaʻai; (2) ka hui placebo e loaʻa ana i ka placebo ma ke ʻano he meaʻai meaʻai; (2)). ʻO ka hui LCPUFA + X i loaʻa i kahi meaʻai meaʻai me ka LCPUFA (loaʻa ka 120 mg ARA, 300 mg DHA a me 100 mg EPA i kēlā me kēia lā) me ka Compound X (ʻaʻole i hōʻike ʻia ʻaʻole kēia pūhui ke kumuhana o kēia haʻawina) ) (3) LCPUFA + LH pūʻulu e loaʻa ana i ka meaʻai meaʻai me LCPUFA (120mg ARA, 300mg DHA a me 100mg EPA i kēlā lā i kēia lā) i hui pū ʻia me LH (10mg lutein a me 2mg zeaxanthin i kēlā me kēia lā).
ʻO ka meaʻai hoʻokolohua a me nā lako no kēia haʻawina i hāʻawi ʻia e Suntory Health Co., Ltd., nāna e kūʻai aku i nā meaʻai olakino i loaʻa iā LCPUFA.
Ua hoʻohana ʻia ka Wechsler Logical Memory Scale II (WMS-R LM II) a me ka Montreal Cognitive Test in Japanese (MoCA-J) no ka nānā ʻana.
Ua hoʻopaʻa ʻia ka makahiki, ke kāne, a me ka hoʻonaʻauao ma ke ʻano he ʻano o nā mea komo. Ua hōʻiliʻili ʻia nā laʻana koko ma ka papa kuhikuhi, nā pule 12 a me 24 no ka ʻakika momona a me ka loiloi LZ.
Ua hana ʻia ka hoʻāʻo ʻana o Neuropsychological a ua ana ʻia ka ʻai ʻana o ka momona momona i ka baseline, ma 12 a me 24 wiki. Hoʻopau kēlā me kēia mea komo i kahi diary, hoʻopaʻa i ka ʻai hou a nānā i nā loli ola nui.
Ua hōʻike ʻia nā mea i ʻike ʻia ʻaʻohe hopena koʻikoʻi o LCPUFA + LZ i ka hana hoʻomanaʻo i nā poʻe Kepani ʻelemakule olakino me nā pilikia hoʻomanaʻo, akā ua hoʻomaikaʻi ka mea hoʻohui i ka hana hoʻomanaʻo i nā poʻe me ka emi ʻana o ka cognitive.
Wahi a nā mea kākau, ʻo nā haʻawina hana e hiki mai ana e pili ana i ka ʻike kikoʻī o ka hana cognitive baseline o nā mea komo e kōkua i ka hoʻoholo kūpono e pili ana i ka hopena o ka hana i ka hana hoʻomanaʻo.
"Ka hopena o nā ʻakika momona polyunsaturated i hui pū ʻia me ka lutein a me ka zeaxanthin ma ka hoʻomanaʻo episodic i nā poʻe ʻelemakule olakino"
Sueyasu, T., Yasumoto, K., Tokuda, H., Kaneda, Y.;
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