Ke hoʻohana nei kahi noiʻi lapaʻau kanaka hou i kahi ʻano ashwagandha i hoʻopaʻa ʻia, ʻo Witholytin, e loiloi i kona hopena maikaʻi ma ka luhi a me ke kaumaha.
Ua loiloi nā kānaka noiʻi i ka palekana o ka ashwagandha a me kona hopena i ka luhi a me ke kaumaha i ʻike ʻia ma 111 mau kāne a me nā wahine olakino i piha i nā makahiki 40-75 i ʻike i nā pae ikehu haʻahaʻa a me ke kaumaha i ʻike ʻia ma waena a kiʻekiʻe ma luna o kahi manawa 12 mau pule. Ua hoʻohana ke aʻo ʻana i kahi mahele o 200 mg o ka ashwagandha ʻelua i ka lā.
Ua hōʻike ʻia nā hopena ua ʻike nā mea komo e lawe ana i ka ashwagandha i ka emi nui ʻana o 45.81% ma nā helu honua Chalder Fatigue Scale (CFS) a me ka emi ʻana o 38.59% i ke kaumaha (perceived stress scale) i hoʻohālikelike ʻia me ka baseline ma hope o 12 mau pule.
Ua hōʻike ʻia nā hopena ʻē aʻe ua piʻi aʻe (hoʻomaikaʻi ʻia) nā helu kino ma ka Patient Reported Outcome Measurement Information System (PROMIS-29) ma 11.41%, ua emi nā helu psychological ma PROMIS-29 (hoʻomaikaʻi ʻia) ma 26.30% a ua piʻi aʻe ma 9 .1% i hoʻohālikelike ʻia me ka placebo. Ua emi ka loli o ka puʻuwai (HRV) ma 18.8%.
Ua hōʻike ʻia ka hopena o kēia haʻawina e hiki i ka ashwagandha ke kākoʻo i kahi ala adaptogenic, hakakā i ka luhi, hoʻoulu hou, a hoʻolaha i ka homeostasis a me ke kaulike.
Ua ʻōlelo nā kānaka noiʻi i komo i ka noiʻi he nui nā pono hoʻoikaika o ka ashwagandha no ka poʻe o waena o ka makahiki a me ka poʻe ʻelemakule kaumaha e ʻike nei i nā pae kiʻekiʻe o ke kaumaha a me ka luhi.
Ua hana ʻia kahi subanalysis e nānā i nā biomarkers hormonal i nā kāne a me nā wahine i komo. Ua hoʻonui nui ʻia ka nui o ke koko o ka testosterone manuahi (p = 0.048) a me ka hormone luteinizing (p = 0.002) ma 12.87% i nā kāne e lawe ana i ka ashwagandha i hoʻohālikelike ʻia me ka hui placebo.
Hāʻawi ʻia i kēia mau hopena, he mea nui e aʻo hou aku i nā hui demographic e pōmaikaʻi paha mai ka lawe ʻana i ka ashwagandha, no ka mea, ʻokoʻa paha kona hopena hoʻemi kaumaha ma muli o nā mea e like me ka makahiki, ke kāne, ke kūlana o ka helu helu kino, a me nā mea hoʻololi ʻē aʻe.
"Ua hauʻoli mākou i ka hoʻohui ʻana o kēia puke hou i nā hōʻike e kākoʻo ana iā Vitolitin me kā mākou kino e ulu nei o nā hōʻike e hōʻike ana i ka hoʻohālikelike ʻana o ka USP o ka ashwagandha extract," wahi a Sonya Cropper, ka hope pelekikena o Verdure Sciences. Ke hoʻomau nei ʻo Cropper, "Ke ulu nei ka hoihoi i ka ashwagandha, nā adaptogens, ka luhi, ka ikehu a me ka hana noʻonoʻo."
Hana ʻia ʻo Vitolitin e Verdure Sciences a hāʻawi ʻia ma ʻEulopa e LEHVOSS Nutrition, he mahele o ka LEHVOSS Group.